Molecular Drug Susceptibility Testing and Genotyping of Mycobacterium leprae Strains from South America
نویسندگان
چکیده
منابع مشابه
Molecular Identification and Conventional Susceptibility Testing of Iranian Clinical Mycobacterium fortuitum Isolates
Objective(s) Rapidly growing mycobacteria (RGM) are capable of producing diseases in humans. Since mycobacteria vary in their susceptibility, precise identification is critical for adoption of correct drug therapy. The main aim of this study was molecular identification and evaluation of antimicrobial susceptibility pattern of Iranian clinically isolated Myocbacterium fortuitum. Materials and...
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BACKGROUND Real-Time PCR-High Resolution Melting (qPCR-HRM) analysis has been recently described for rapid drug susceptibility testing (DST) of Mycobacterium leprae. The purpose of the current study was to further evaluate the validity, reliability, and accuracy of this assay for M. leprae DST in clinical specimens. METHODOLOGY/PRINCIPAL FINDINGS The specificity and sensitivity for determinin...
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Although the prevalence of leprosy has significantly decreased since the introduction of theWorld Health Organization (WHO) regimen of multidrug therapy (MDT), the incidence remains high, with a report of approximately 215 656 cases globally in 2013. Among these, 126 913 cases were reported from India alone [1]. Of a total number of 3196 relapse cases, India alone contributed 486 cases [1]. For...
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ژورنال
عنوان ژورنال: Antimicrobial Agents and Chemotherapy
سال: 2011
ISSN: 0066-4804,1098-6596
DOI: 10.1128/aac.00201-11